Two brothers: Cicero Grimes - freelance psychiatrist and one-man detox unit in America's white trash Deep South; and Luther Grimes - bad news Vietnam veteran and smack dealer. They hate each other, and only they know why.
Ex-hooker and coke head Callie Carter is on the run - with one million dollars stolen from her evangelist husband's bank.
Corrupt, Sadistic police captain Clarence Jefferson wants to get his hands on the preacher's money. But even more, he wants to break Cicero apart, to find out the real reason why he has spent years hunting his brother like a mad dog.