Organic Structure Determination Using 2-D NMR Spectroscopy: A Problem-Based Approach, Second Edition, provides an introduction to the use of two-dimensional (2-D) nuclear magnetic resonance (NMR) spectroscopy to determine organic structure. The book begins with a discussion of the NMR technique, while subsequent chapters cover instrumental considerations; data collection, processing, and plotting; chemical shifts; symmetry and topicity; through-bond effects; and through-space effects. The book also covers molecular dynamics; strategies for assigning resonances to atoms within a molecule; strategies for elucidating unknown molecular structures; simple and complex assignment problems; and simple and complex unknown problems. Each chapter includes problems that will enable readers to test their understanding of the material discussed.
Presents strategies for assigning resonances to known structures and for deducing structures of unknown organic molecules based on their NMR spectraContains 30 known and 30 unknown structure determination problemsFeatures a supporting website from which instructors can download the structures of the unknowns in selected chapters, digital versions of all figures, and raw data sets for processing