There's a killer on the road, and nobody is safe.
Michael and Megan Fitzgerald are siblings who share a terrifying past. Both adopted, and now grown - Michael is a long-haul truck driver, Megan a college student majoring in psychology -- they trust each other before anyone else. They've had to.
When a young woman is found murdered in Michael's LA apartment, he becomes the chief suspect and is quickly apprehended. But then there's another killing that is strikingly similar. And another. And not just in LA - as the spree spreads across the country, the FBI become involved in a manhunt for a cold-blooded serial killer.
The murders are clearly linked, but the killer is more ingenious than anyone could expect, and false leads will leave the LAPD and FBI completely baffled at how to prevent a string of murders that seem unstoppable.