Deborah Crombie was born in Dallas and dropped out of high school at sixteen. She graduated from Austin College in Sherman, Texas, with a degree in biology.
She then worked in advertising and newspapers, and attended the Rice University Publishing Program. A post-university trip to England, however, cemented a life-long passion for Britain, and she later immigrated to the UK.
A Share in Death , was subsequently given Agatha and Macavity nominations for Best First Novel of 1993. The fifth novel, Dreaming of the Bones (Scribner 1997), a New York Times Notable Book for 1997, was short-listed by Mystery Writers of America for the 1997 Edgar Award for Best Novel, won the Macavity award for Best Novel, and was voted by the Independent Mystery Booksellers Association as one of the hundred best mysteries of the century. Her subsequent novels have been received with critical acclaim and are widely read internationally, particularly in Germany.